Uso de plantas medicinales como una alternativa para el tratamiento de la fasciolasis

Autores/as

  • Joseline Licona-Hernández Universidad Autónoma del Estado de Hidalgo, Instituto de Ciencias Agropecuarias, Área académica de Medicina Veterinaria y Zootecnia, rancho Universitario avenida Universidad km 1, Ex-Hacienda de Aquetzalpa, Tulancingo, Hidalgo, México, C. P. 43600. https://orcid.org/0009-0004-7581-3687
  • José Ignacio Olave-Leyva Universidad Autónoma del Estado de Hidalgo, Instituto de Ciencias Agropecuarias, Área académica de Medicina Veterinaria y Zootecnia, rancho Universitario avenida Universidad km 1, Ex-Hacienda de Aquetzalpa, Tulancingo, Hidalgo, México, C. P. 43600. https://orcid.org/0000-0002-4440-2138
  • Deyanira Ojeda-Ramírez Universidad Autónoma del Estado de Hidalgo, Instituto de Ciencias Agropecuarias, Área académica de Medicina Veterinaria y Zootecnia, rancho Universitario avenida Universidad km 1, Ex-Hacienda de Aquetzalpa, Tulancingo, Hidalgo, México, C. P. 43600. https://orcid.org/0000-0003-4649-2699

DOI:

https://doi.org/10.29059/cienciauat.v19i1.1846

Palabras clave:

Fasciola, plantas medicinales, extractos, metabolitos secundarios

Resumen

La fascioliasis es una enfermedad causada por gusanos planos, parásitos de la clase trematoda y género Fasciola, que afecta a animales y humanos. A pesar de su considerable impacto en la salud pública y el sector pecuario, así como a su frecuente reaparición, se encuentra entre las enfermedades tropicales desatendidas. Aunado a ello, el uso indiscriminado de fasciolicidas sintéticos en el ganado ha propiciado resistencia de este trematodo a los antihelmínticos disponibles en el mercado, por lo que es necesario contar con nuevas alternativas de tratamiento. El objetivo de este trabajo fue analizar los avances recientes a nivel mundial sobre las plantas medicinales con efecto sobre Fasciola, reportadas en las bases de datos PubMed, Scopus, SciFinder y Google Scholar, entre enero de 2019 y julio de 2023. Se encontraron reportes sobre el potencial fasciolicida de 32 plantas, 7 de ellas con actividad sobre huevos, 3 sobre los estadios larvales, 1 sobre juveniles y el resto sobre el estadio adulto del parásito. Dentro de los metabolitos secundarios responsables de la actividad farmacológica, se han identificado monoterpenos, alcaloides, ácidos grasos poliinsaturados (PUFA’s), artemisina y compuestos fenólicos; destacando la curcumina y la timoquinona. Los resultados encontrados ponen de manifiesto el potencial uso de las plantas como fuente de nuevos principios activos fasciolicidas.

Citas

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Publicado

2024-03-22

Cómo citar

Licona-Hernández, J. ., Olave-Leyva, J. I., & Ojeda-Ramírez, D. (2024). Uso de plantas medicinales como una alternativa para el tratamiento de la fasciolasis. CienciaUAT, 19(1), 61–73. https://doi.org/10.29059/cienciauat.v19i1.1846

Número

Sección

Biología y Química

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