Antioxidant and immunostimulant properties of polyphenols in carnivorous farmed fish

Authors

  • Cynthia Esmeralda Lizárraga-Velázquez Centro de Investigación en Alimentación y Desarrollo (CIAD), A.C., Laboratorio de Nutrición y Alimentación de Peces y Crustáceos, Av. Sábalo-Cerritos S/N, Estero del Yugo, Mazatlán, Sinaloa, México, C.P. 82000.
  • Crisantema Hernández Centro de Investigación en Alimentación y Desarrollo (CIAD), A.C., Laboratorio de Antioxidantes y Alimentos Funcionales.
  • Gustavo Adolfo González-Aguilar Centro de Investigación en Alimentación y Desarrollo (CIAD), A.C., Laboratorio de Antioxidantes y Alimentos Funcionales.
  • José Basilio-Heredia Centro de Investigación en Alimentación y Desarrollo (CIAD), A.C., Laboratorio de alimentos funcionales y nutracéuticos.

DOI:

https://doi.org/10.29059/cienciauat.v12i2.904

Keywords:

aquaculture, oxidative stress, innate immune system, antioxidant enzymes, functional food.

Abstract

 

Fish production by intensive aquaculture, is an economically important strategy to produce food. However, intensive sh farming generates oxidative stress and suppress the immune system, causing loss of product quality and increasing  sh mortality rates. To diminish these effects, plants as a source of polyphenols with antioxidants and immunostimulant properties were administered to carnivorous farmed  sh. The aim of this study was to describe the effects of plant polyphenols as antioxidants and immunostimulants on carnivorous  sh, and to promote their use as functional ingredients in aquaculture. Plants as a source of polyphenols showed the ability to improve the immune and antioxidant defense systems of the analyzed species, resulting in a tissue of better nutritional quality and a higher endogenous antioxidant content. However, the biological properties of polyphenols are dependent on the type of plant and their concentration within it, the dose and the time of administration, as well as the food matrix, which determines their bioaccessibility and bioavailability in the organism. There is little information on the effec of polyphenols in post mortem quality; therefore, further studies should be conducted.

 

Author Biography

Crisantema Hernández, Centro de Investigación en Alimentación y Desarrollo (CIAD), A.C., Laboratorio de Antioxidantes y Alimentos Funcionales.

RESPONSABLE DEL LABORATORIO DE NUTRICION ACUICOLA

INVESTIGADOR TITULAR C

SNI 2

DPTO. ACUACULTURA Y MANEJO AMBIENTAL

References

Aboonabi, A. and Singh, I. (2015). Chemopreventive role of anthocyanins in aterosclerosis via activation of Nrf2-ARE as an indicator and modulator of redox. Biomedicine and Pharmacotherapy. 72: 30-36.

Abdel-Tawwab, M., Ahmad, M. H., Seden, M. E. A., and Sakr, S. F. M. (2010). Use of green tea, Camellia sinensis L., in practical diet for growth and protection of nile tilapia, Oreochromis niloticus (L.), against Aeromonas hydrophila Infection. Journal of the World Aquaculture Society. 41(S2): 203-213.

Aboul-Enein, A. M., Salama, Z. A., Gaafar, A. A., Aly, H. F., A-bou-Elella, F., and Ahmed, H. A. (2016). Identification of phenolic compounds from banana peel (Musa paradaisica L.) as antioxidant and antimicrobial agents. Journal of Chemical and Pharmaceutical Research. 8(4): 46-55.

Aditya, S., Ahammed, M., Jang, S. H., and Ohh, S. J. (2017). Effects of dietary onion (Allium cepa) extract supplementation on performance, apparent total tract retention of nutrients, blood profile and meat quality of broiler chicks. Asian-Australasian Journal of Animal Sciences. 30(2): 229-235.

Afzal, M., Safer, A. M., and Menon, M. (2015). Green tea polyphenols and their potencial role in health and disease. In ammopharmacology. 23(4): 151-161.

Akrami, R., Gharaei, A., Mansour, M. R., and Galeshi, A. (2015). Effects of dietary onion (Allium cepa) powder on growth, innate immune response and hemato-biochemical parameters of beluga (Huso huso Linnaeus, 1754) juvenile. Fish Shellfish Immunology. 45(2): 828-834.

Alexander, C. P., Kirubakaran, C. J. W. and Michael, R. D. (2010). Water soluble fraction of Tinospora cordifolia leaves enhanced the non-specific immune mechanisms and disease resistance in Oreochromis mossambicus. Fish & shell sh immunology. 29(5): 765-772.

Ayala, A., Muñoz, M. F., and Argüelles, S. (2014). Lipid peroxidation: production, metabolism, and signaling mechanisms of malondialdehyde and 4-Hydroxy-2-none- nal. Hindawi Publishing Corporation. 2014: 1-32.

Barrera, G. (2012). Oxidative stress and lipid peroxidation products in cancer progression and therapy. ISRN Oncology. 1-21.

Blancas-Benítez, F. J., Mercado-Mercado, G., Quirós-Sauceda, A. E., Montalvo-González, E., González-Aguilar, G. A., and Sáyago-Ayerdi, S. G. (2015). Bioaccessibility of polyphenols associated with dietary ber and in vitrokinetics release of polyphenols in Mexican Ataulfo mango(Mangifera indica L.) by-products. Food & Function. 6(3): 859-868.

Bravo, L. (1998). Polyphenols: Chemistry, dietary sources, Metabolism, and Nutrititional Signi cance. Nutrition Reviews. 56(11): 317-333.

Bulfon, C., Donatella, V., and Galeotti, M. (2013). Current research on the use of plant-derived products in farmed fish. Aquaculture Research. 46(3): 1-39.

Buonocorea, F., Randellia, E., Trisolinoa, P., Facchianob, A., de-Pascalec, D., and Scapigliati, G. (2014). Molecular characterization, gene structure and antibacterial activity of a g-type lysozyme from the European sea bass (Dicentrarchus labrax L.). Molecular Immunology. 62(1): 10-18.

Carlo, G. D., Mascolo, N., Izzo, A. A., and Capasso, F. (1999). Flavonoids: old and new aspects of a class of natural therapeutic drugs. Life Sciences. 65(4): 337-353.

Catap, E. S., Jimenez, M. R. R., and Tumbali, P. B. (2015). Immunostimulatory and antioxidative properties of corn silk from zea mays L. in Nile tilapia, Oreochromis niloticus. International Journal of Fisheries and Aquaculture. 7(3): 30-36.

Chakraborty, S. B. and Hancz, C. (2011). Application of phytochemicals as immunostimulant, antipathogenic and antistress agents in finfish culture. Reviews in Aquaculture. 3(3): 103-119.

Cho, H. C. and Lee, S. M. (2012). Onion powder in the diet of the Olive ounder (Paralichthys olivaceus): Effects on the growth, body composition and lysozyme activity. Journal of the World Aquaculture Society. 43(1): 30-38.

Chu, H., Tang, Q., Huang, H., Hao, W., and We, X. (2016). Grape-seed proanthocyanidins inhibit the lipopolysac-charide-inducedin ammatory mediator expression in RAW264.7 macrophages bysuppressing MAPK and NF-κb signal pathways. Environmental Toxicology and Pharmacology. 41: 159-166.

Domanski, M. J., Fuster, V., Diaz-Mitoma, F., Grundy, S., Lloyd-Jones, D., Mamdani, M., ..., and Udell, J. A. (2015). Next steps in primary prevention of coronary heart disease: rationale for and design of the ECAD trial. Journal of the American College of Cardiology. 66(16): 1828-1836.

Done, H. Y., Venkatesan, A. K., and Halden, R. U. (2015). Does the recent growth of aquaculture create antibiotic resistance threats different from those associated with land animal production in agriculture?. The AAPS journal. 17(3): 513-524.

Galego, L. R., Jockusch, S., and Da-Silva, J. P. (2013). Polyphenol and volatile profiles of pomegranate (Punica granatum L.) fruit extracts and liquors. International Journal of Food Science and Technology. 48(4): 693-700.

Giomaro, G., Karioti, A., Bilia, A. R., Bucchini, A., Giamperi, L., Ricci, D., and Fraternale, D. (2014). Polyphenols profile and antioxidant activity of skin and pulp of a rare apple from Marche región (Italy). Chemistry Central Journal. 8(1): 45.

Hamre, K., Christiansen, R., Waagbø, R., Maage, A., Torstensen, B. E., Lygren, B., ..., and Albrektsen, S. (2004). Antioxidant vitamins, minerals and lipid levels in diets for Atlantic salmon (Salmo salar L.): effects on growth performance and fillet quality. Aquaculture Nutrition. 7(10): 113-123.

Harikrishnan, R., Balasundaram, C., and Heo, M. S. (2011). Influence of diet enriched with green tea on innate humoral and celular immune response of kelp grouper (Epinephelus bruneus) to Vibrio carchariae infection. Fish Shellfish immunology. 30(3): 972-979.

Harikrishnan, R., Heo, J., Balasundaram, C., Kim, M. C., Kim, S. J., Han, Y. K., and Heo, M. S. (2010). Effect of Punica granatum solvent extracts on immune system and disease resistance in Paralichthys olivaceus against lymphocystis disease virus (LDV). Fish Shellfish Immunology. 29(4): 668-673.

Harikrishnan, R., Kim, J. S., Kim, M. C., Balasundaram, C., and Heo, M. S. (2012). Pomegranate enriched diet enhances the hematology, innate immune response, and disease resistance in olive ounder against Philasterides dicentrarchi. Veterinary Parasitology. 187(1): 147-156.

Hasanpour, S., Salati, A. P., Falahatkar, B., and Azarm, H. M. (2017). Effects of dietary green tea (Camelia sinensis L.) supplementation on growth performance, lipid metabolism, and antioxidant status in a sturgeon hybrid of Sterlet (Huso huso ♂ × Acipenser ruthenus ♀) fed oxidized fish oil. Fish Physiology and Biochemistry. 43(4): 1315-1323.

Hwang, J. H., Lee, S. W., Rha, S. J., Yoon, H. S., Park, E. S., Han, K. H., and Kim, S. J. (2013). Dietary green tea extract improves growth performance, body composition, and stress recovery in the juvenile black rock sh, Sebastes schlegeli. Aquaculture International. 21(3): 525-538.

Kosinska, A., Karamac, M., Estrella, I., Hernández, T., Bartolomé, B., and Dykes, G. A. (2012). Phenolic compounds pro les and antioxidant capacity of Persea americana Mill. Peels and sedes of two varieties. Journal of Agricultural and Food Chemistry. 60(18): 4613-4619.

Kumar, S. and Pandey, A. K. (2013). Chemistry and biological activities of avonoids: An overview. The Scientific World Journal. 1-16.

Kumar, V. P., Prashanth, K. V., and Venkatesh, Y. P. (2015). Structural analyses and immunomodulatory properties of fructo-oligosaccharides from onion (Allium cepa). Carbohydrate Polymers. 117: 115-22.

Lushchak, V. I. (2011). Environmentally induced oxidative stress in aquatic animals. Aquatic Toxicology. 101(1): 13-30.

Lushchak, V. I. (2014). Free radicals, reactive oxygen species, oxidative stress and its classi cation. Chemico-Biological Interactions. 224: 164-175.

Magnadóttir, B. (2010). Immunological control of fish diseases. Marine Biotechnology. 12(4): 361-379.

Magrone, T., Fontana, S., Laforgia, F., Dragone, T., Jirillo, E., and Passantino, L. (2016). Administration of polyphenol-enriched feed to farmed sea bass (Dicentrarchaus Labrax L.) modulates intestinal and spleen immune responses. Oxidative Medicine and Cellular Longevity. 2: 1-11.

Makris, D. P. and Kefalas, P. (2013). Characterization of polyphenolic phytochemicals in red grape pomace. International Journal of Waste Resources. 3(2): 126.

Martínez-Álvarez, R. M., Morales A. E., and Sanz, A. (2005). Antioxidant defense in sh: biotic and abiotic factors. Reviews in Fish Biology and Fisheries. 15(1-2): 75-88.

Moon, J., Lee, S., Do, H. J., Cho, Y., Chung, J. H., and Shin, M. J. (2012). Quercetin up-regulates LDL receptor expression in HepG2 cells. Phytotherapy Research. 26(11): 1688-1694.

Murthy, P. S. and Naidu, M. M. (2012). Recovery of phenolic antioxidants and functional compounds from coffee industry by-products. Food and Bioprocess Technology. 5(3): 897-903.

Nootash, S., Sheikhzadeh, N., Baradaran, B., Oushani, A. K., Moghadam, M. R. M., Nofouzi, K., and Shabanzadeh, S. (2013). Green tea (Camelia sinensis) administration induces expression of immune relevant genes and biochemical parameters in rainbow trout (Oncorhynchus mykiss). Fish Shell sh immunology. 35(6): 1916-1923.

Oliveira, T. T., Campos, K. M., Cerqueira-Lima, A. T., Cana-Brasil-Carneiro, T., da-Silva-Velozo, E., ..., and Fi-gueiredo, C. A. (2015). Potential therapeutic effect of Allium cepa L. and quercetin in a murine model of Blomia tropicalis induced asthma. DARU Journal of Pharmaceutical Sciences. 23(1): 1-12.

Onakpoya, I., Spencer, E., Heneghan, C., and Thompson, M. (2014). The effect of green tea on blood pressure and lipid pro le: a systematic review and meta-analysis of randomized clinical trials. Nutrition, Metabolism and Cardiovascular Diseases. 24(8): 823-836.

Patel, S. and Vajdy, M. (2015). Induction of cellular and molecular immunomodulatory pathways by vitamin A and Flavonoids. Expert Opinion on Biological Therapy. 15(10): 1411-1428.

Philip, A. M. and Vijayan, M. M. (2015). Stress-immune-growth interactions: cortisol modulates suppressors of cytokine signaling and JAK/STAT pathway in rainbow trout liver. PLoS One. 10(6): 1-18.

Rafehi, H., Ververis, K., and Karagiannis, T. C. (2012). Mechanisms of action of phenolic compounds in olive. Journal of Dietary Supplements. 9(2): 96-109.

Ramos-Escudero, F., Muñoz, A. M., Alvarado-Ortiz, C., Alvarado, A., and Yañez J. A. (2012). Purple Corn (Zea ma- ys L.) Phenolic compounds pro le and its assessment as an agent against oxidative stress in isolated mouse organs. Journal of medicinal Food. 15(2): 206-215.

Reverter, M., Bontemps, N., Lecchini, D., Banaigs, B., and Sasal, P. (2014). Use of plant extracts in fish aquaculture as an alternative to chemotherapy: Current status and future perspectives. Aquaculture. 433: 50-61.

Ross, G. R., Selvasubramanian, S., and Jayasundar, S. (2001). Immunomodulatory activity of Punica granatum in rabbits-a preliminary study. Journal of Ethnopharmacology. 78(1): 85-87.

Sahu, S., Das, B. K., Pradhan, J., Mohapatra, B. C., Mishra, B. K., and Sarangi, N. (2007). Effect of Mangifera indica kernel as a feed additive on immunity and resistance to Aeromonas hydrophila in Labeo rohita in finngerlings. Fish Shellfish Immunology. 23(1): 109-118.

Servili, M., Sordini, B., Esposto, S., Urbani, S., Venezia- ni, G., Di-Maio, I., ..., and Taticchi, A. (2013). Biological activities of phenolic compounds of extra virgin olive oil. Antioxidants. 3(1): 1-23.

Shahidi, F. and Ambigaipalan, P. (2015). Phenolics and polyphenolics in foods, beverages and spices: Antioxidant activity and health effects- A review. Journal of Functional Foods. 18: 820-897.

Shalaby, E. A. and Shanab, S. M. M. (2013). Antioxidant compounds, assays of determination and mode of action. African Journal of Pharmacy and Pharmacology. 7(10): 528-539.

Shin, H. S., Yoo, J. H., Min, T. S., Lee, K. Y., and Choi, C. Y. (2010). The effects of quercetin on physiological characteristics and oxidative stress resistance in olive flounder, Paralichtys olivaceus. Asian Australasian Journal of Animal Sciences. 23(5): 588-597.

Sicuro, B., Dapra, F., Gail, F., Palmegiano, G. B., Schiavone, R., Zilli, L., and Vilella, S. (2010). Olive oil by-product as a natural antioxidant in Gilthead sea bream (Sparus aurata) nutrition. Aquaculture International. 18(4): 511-522.

Sunyer, J. O. (2013). Fishing for mammalian paradigms in the teleost immune system. Nature Immunology. 14(4): 320-326.

Thawonsuwan, J., Kiron, V., Satoh, S., Panigrahi, A., and Verlhac, V. (2010). Epigallocatechin-3-gallate (EGCG) a effects the antioxidant and immune defense of the rainbow trout, Oncorhynchus mykiss. Fish Physiology Biochemistry. 36(3): 687-697.

Todorcevic, M., Kjær, M. A., Djakovic, N., Vegusdal, A., Torstensen, B. E., and Ruyter, B. (2009). N-3 HUFAs a effect fat deposition, susceptibility to oxidative stress, and apoptosis in Atlantic salmon visceral adipose tissue. Comparative Biochemistry and Physiology Part B. 152(2): 135-143.

Vaseeharan, B. and Thaya, R. (2014). Medicinal plant derivates as immunostimulants: an alternative to chemo- therapeutics and antibiotics in aquaculture. Aquaculture International. 22(3): 1079-1091.

Velderrain-Rodríguez, G. R., Palafox-Carlos, H., Wall- Medrano, A., Ayala-Zavala, J. F., Chen, C. Y. O., Robles- Sánchez, M., ..., and González-Aguilar, G. A. (2014). Phenolic compounds: their journey after intake. Journal of Functional Foods. 5(2): 189-197.

Villasante, A., Patro, B., Chew, B., Becerra, M., Wacyk, J., Overturf, K., ..., and Hardy, R. W. (2015). Dietary intake of purple corn extract reduces fat body content and improves antioxidant capacity and n-3 polyunsaturated fatty acid pro le in plasma of rainbow trout, Oncorhynchus mykiss. Journal of the World Aquaculture Society. 46(4): 381-394.

Wang, A. M., Tidrick, C. L., Haque, M., and Stuehr, D. J. (2013). Green tea polyphenols decrease enzyme activity of nitric oxide synthase. The FASEB Journal. 27(1): 790.14.

Zou, J. and Secombes, C. J. (2016). The function of sh cytokines. Biology. 5(2): 23.

Zhou, J., Lin, Y., Ji, H., and Yu, H. (2016). The e ect of green tea waste on growth and health of grass carp (Ctenopharyngodon idellus). Turkish Journal of Fisheries Aquatic Sciences. 16(3): 679-689.

Zhou, K. and Ra oul J. J. (2012). Potential anticancer properties of grape antioxidants. Journal Oncology. 5: 1-8.

Published

2018-01-31

How to Cite

Lizárraga-Velázquez C. E., Hernández, C., González-Aguilar G. A., & Basilio-Heredia, J. (2018). Antioxidant and immunostimulant properties of polyphenols in carnivorous farmed fish. CienciaUAT, 12(2), 127–136. https://doi.org/10.29059/cienciauat.v12i2.904

Issue

Section

Biotechnology and Agricultural Sciences

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