Prevalence and resistance profile to antibiotics of diabetic foot infections isolated microorganisms

Authors

  • Virgilio Bocanegra-García Centro de Biotecnología Genómica. Instituto Politécnico Nacional, boulevard del Maestro s/n, esq. Elías Piña, col. Narciso Mendoza. Reynosa, Tamaulipas, México, C.P. 88710.
  • Guillermo Hernández-Gracía Unidad Médica de Especialistas, González 1 y 2 Zona Centro No. 126, Matamoros, Tamaulipas, México, C.P. 87300.
  • Rubén Celerino Cantú-Ramírez Universidad Autónoma de Tamaulipas, UAM Reynosa Aztlán, Calle 16 y Lago de Chapala, col. Aztlán Reynosa, Tamaulipas, México, C.P. 88740.
  • Arely Díaz-López Universidad Autónoma de Tamaulipas, UAM Reynosa Aztlán, Calle 16 y Lago de Chapala, col. Aztlán Reynosa, Tamaulipas, México, C.P. 88740
  • Selene Ávila-Aguilar 1Unilab Laboratorio de Análisis Clínicos y Servicios de Referencia, Rayón 6 y 7 No. 600, Zona Centro, H. Matamoros, Tamaulipas, México, C.P. 87300.
  • Alejandro Espinoza-Tavera Unilab Laboratorio de Análisis Clínicos y Servicios de Referencia, Rayón 6 y 7 No. 600, Zona Centro, H. Matamoros, Tamaulipas, México, C.P. 87300.
  • Edgar Alonso García-García Unidad Médica de Especialistas, González 1 y 2 Zona Centro No. 126, Matamoros, Tamaulipas, México, C.P. 87300.
  • Gildardo Rivera-Sánchez Centro de Biotecnología Genómica. Instituto Politécnico Nacional, boulevard del Maestro s/n, esq. Elías Piña, col. Narciso Mendoza. Reynosa, Tamaulipas, México, C.P. 88710.

DOI:

https://doi.org/10.29059/cienciauat.v9i1.628

Keywords:

diabetic foot, infections, drug-resistance.

Abstract

Diabetes mellitus (DM) is a chronic disease that affects a considerable portion of the population and type 2 diabetes represents a serious current public health problem in Mexico. Diabetic foot is a severe consequence of diabetes for its prevalence, the frequency of resulting infections, and the high social and economic costs. In this study we examined 382 isolated families of infections in 284 patients to determine their identity by biochemical tests and their drug resistance profile. Of the 382 isolates, 186 samples (48.6 %) were positive Gram bacteria; 182 samples (47.6 %) were negative Gram bacteria; and 14 (3.6 %) were Candida sp. In 158 of the 284 samples (55.6.%) only one type of bacteria was identified; in 113 samples (39.7 %) a mixed culture was found, with 7 samples containing both bacteria and yeast and 13 samples resulting negative. The most prevalent pathogens were Staphylococcus aureus and Pseudomonas aeruginosa. In S. aureus isolates, 63.9 % was resistant to MRSA; 4.1 % was resistant to vancomicyn; and 18.6 % was resistant to imepenem. P. aeruginosa was the most prevalent Gram negative isolated and also the one with the most drug resistance. Drug-resistance analysis showed that the majority of S. aureus were MRSA and in P. aeruginosa, families resistant to all tested antimicrobials prevailed.

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How to Cite

Bocanegra-García, V., Hernández-Gracía, G., Cantú-Ramírez, R. C., Díaz-López, A., Ávila-Aguilar, S., Espinoza-Tavera, A., García-García, E. A., & Rivera-Sánchez, G. (2014). Prevalence and resistance profile to antibiotics of diabetic foot infections isolated microorganisms. CienciaUAT, 9(1), 84-89. https://doi.org/10.29059/cienciauat.v9i1.628

Issue

Vol. 9 No. 1: July-December 2014

Section

Medicine and Health Sciences